Autoimmune diseases


Zuzana Paračková, M.Sc.

Irena Zentsová, M.Sc.

Jitka Smetanová, M.Sc.

Senior Scientists/Clinicians

Prof. Anna Šedivá, M.D., Ph.D.

Tomáš Milota. M.D., Ph.D.

Lab Technicians

Michal Rataj, M.Sc.



Novel XIAP mutation causing enhanced spontaneous apoptosis and disturbed NOD2 signalling in a patient with atypical adult-onset Crohn's disease
Cell Death Dis. 2020 Jun 8;11(6):430. doi: 10.1038/s41419-020-2652-4.

Neutrophil Extracellular Trap Induced Dendritic Cell Activation Leads to Th1 Polarization in Type 1 Diabetes
Front Immunol. 2020 Apr 14;11:661. doi: 10.3389/fimmu.2020.00661. eCollection 2020.

Enhanced STAT3 phosphorylation and PD-L1 expression in myeloid dendritic cells indicate impaired IL-27R alpha signaling in type 1 diabetes
Sci Rep. 2020 Jan 16;10(1):493. doi: 10.1038/s41598-020-57507-8.

Anti-IL6 Autoantibodies in an Infant With CRP-Less Septic Shock
Front Immunol. 2019 Nov 8;10:2629. doi: 10.3389/fimmu.2019.02629.

Mutual alteration of NOD2-associated Blau syndrome and IFNγR1 deficiency
J Clin Immunol. 2020 Jan;40(1):165-178. doi: 10.1007/s10875-019-00720-6. Epub 2019 Nov 23.

Changes in innate and adaptive immunity over the first year after the onset of type 1 diabetes
Acta Diabetol. 2020 Mar;57(3):297-307. doi: 10.1007/s00592-019-01427-1. Epub 2019 Sep 30.

Data on microbial DNA-induced IL-1β production in monocytes of type 1 diabetes patients
Data Brief. 2019 Jul 27;25:104321. doi: 10.1016/j.dib.2019.104321.

Monocytes contribute to DNA sensing through the TBK1 signaling pathway in type 1 diabetes patients
J Autoimmun. 2019 Dec;105:102294. doi: 10.1016/j.jaut.2019.06.005. Epub 2019 Jun 28

Alteration of B cell subsets and the receptor for B cell activating factor (BAFF) in paediatric patients with type 1 diabetes
Immunol Lett. 2017 Sep;189:94-100. doi: 10.1016/j.imlet.2017.04.009. Epub 2017 Apr 14.

T regulatory lymphocytes in type 1 diabetes: Impaired CD25 expression and IL-2 induced STAT5 phosphorylation in pediatric patients
Autoimmunity. 2016 Dec;49(8):523-531. doi: 10.1080/08916934.2016.1217998. Epub 2016 Aug 25.





Created: 19. 11. 2020 / Modified: 23. 11. 2020 / Responsible person: RNDr. Jan Lašťovička, CSc.