Department of Immunology
Research projects
This year, the highly popular Spring PID School took place on April 18.-20., 2024. A report and a photogallery from this event organized by the primary immunodeficiency working group at the Department of Immunology, 2nd Faculty of Medicine, Charles University and Motol University Hospital, headed by prof. Šedivá, Dr. Bloomfield and Dr. Klocperk, can be found here.
The primary immunodeficiency group with the Department of Immunology, 2nd Faculty of Medicine, Charles University and University Hospital in Motol organized an international meeting of clinicians and researchers working in the field of primary immunodeficiencies, which took place in Kutna Hora from May 11th to May 13. For more (...)
On May 19th-21st, 2022, the traditional Spring PID School organized by the team of prof. Sediva took place in Kutna Hora. This year, the participants included both domestic and international doctors and researchers, as well as two undergraduate students from the 2nd Faculty of Medicine. More information, photos and programme can be found at the event page here.
Dr. Parackova received the Czech immunological society and Jaroslav Sterzl award for her publication "Neutrophil Extracellular Trap Induced Dendritic Cell Activation Leads to Th1 Polarization in Type 1 Diabetes".
Dr. Markéta Bloomfield and her colleagues were interviewed on the CT24 channel's Země v nouzi series about various aspects of the COVID-19 disease.
View the interview here.
The traditional ESID Spring (or in this case Fall) school took place in Kutná hora on November 25-26th, in a hybrid format.
For more information, photos and a programme see here.
[RECRUITMENT DISCONTINUED]
Our thanks to all volunteers, recruitment to the study has now been discontinued.
[RECRUITMENT DISCONTINUED]
The team of physicians at the Department of Immunology, 2nd Faculty of Medicine, Charles University in Prague and University Hospital in Motol, under the leadership of Prof. Anna Sediva, works together with the international scientific group COVID Human Genetic Effort lead by Prof. Jean-Laurent Casanova trying to identify factors influencing the resistance or susceptibility to COVID-19 in humans.
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Every year, the Neuron foundation awards the Neuron Prize to excellent czech scientists. This year, three prizes were awarded for life-long contribution to science, seven prizes were awarded to young scientists and a new prize was awarded for excellence in connecting business and science.
MUDr. Adam Klocperk Ph.D.'s article "Exhausted phenotype of follicular CD8 T cells in CVID" received the Czech Society for Analytical Cytometry's award for the best publication in clinical or applied research published in the year 2020.
Unfortunately, the Eastern Spring School 2020 scheduled for April 23 -25, has been cancelled because of the Covid-19 pandemic.
We had to reschedule our April 2020 event to April 2021.
Physicians and scientists of the Department of Immunology actively participate in the world-wide fight against COVID-19. We work together with top international partners to identify genetic factors predisposing otherwise healthy humans to severe course of the disease (for example as part of the consortium https://www.covidhge.com/), with biotech companies to map the development of immune response to the virus (e.g. as part of the initiative https://www.exbio.cz/about-exbio/covid-19) and received funding support as part of the Modern therapies program from the University Hospital in Motol for the project "Innate immune response to SARS-CoV-2 infection".
The manuscript "Allergy to egg in the cohort of 80 Czech infants with food allergy and the natural history of egg allergy" (http://www.tigis.cz/images/stories/Alergie/2019/2_2019/kopelentova_2_19.pdf) by MUDr. Eliška Kopelentová and the manuscript "First thymic transplant in the Czech Republic as a novel therapeutic option for patients with complete DiGeorge syndrome" (http://www.tigis.cz/images/stories/Alergie/2019/Alergie_4_2019/Alergie4_2019_klocperk.pdf) by MUDr. Adam Klocperk, Ph.D. received the award for best works published in the peer-reviewed journal "Alergie" (http://www.tigis.cz/alergie) during the year 2019. Congratulations!
In collaboration with our colleagues from the Department of Pediatrics we published our manuscript "Changes in innate and adaptive immunity over the first year after the onset of type 1 diabetes" in the international peer-reviewed journal Acta Diabetologica (impact factor 2,99). This work described the development of the immune system in children during the first year after onset of autoimmune diabetes mellitus (T1D) and analyses the relationsthips between immune parameters and course of the disease. This manuscript resulted from the Modern therapy funding program of the University Hospital in Motol. More information about the paper can be found at https://www.ncbi.nlm.nih.gov/pubmed/31570993
EN Doc. Jitka Fučíková převzala cenu Milana Pospíšila a Mario Campy za článek v časopise Cancer Immunology and Immunotherapy: Phase I/II trial of dendritic cell-based active cellular immunotherapy with DCVAC/Pca in patients with rising PSA after primary prostactetomy or salvage radiotherapy for the treatment of prostate cancer.
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